Convey to your medical professional For anyone who is pregnant or Feel you might be pregnant. For the duration of pregnancy, this solution will not be encouraged. It could harm an unborn little one. Talk to your medical professional with regards to the challenges and benefits of this medication. See also Warning part.
Neonatal Opioid Withdrawal Syndrome: Prolonged use for the duration of pregnancy may end up in neonatal opioid withdrawal syndrome, which can be daily life-threatening if not recognized and handled, and requires management In line with protocols designed by neonatology authorities.
Browse the Medication Tutorial provided by your pharmacist Before you begin getting promethazine/phenylephrine/codeine and each time you receive a refill. Should you have any concerns, inquire your doctor or pharmacist.
Health care providers are strongly encouraged: to accomplish a REMS-compliant education software; counsel clients and/or their caregivers, with just about every prescription, on Risk-free use, severe dangers, storage, and disposal; emphasize to sufferers as well as their caregivers the value of reading the Medication Guideline each time it really is supplied by their pharmacist; and look at other applications to boost affected individual, residence, and Local community safety.
Cocaine of this type need to readily submit to facile atomization and granular submission. As with all cocaine, humidity renders the fishscale powder recalcitrant and of clumpy Structure.
Get medical enable immediately if check here you detect any of the following: sluggish/shallow breathing, severe drowsiness/trouble waking up, confusion.
INDICATIONS AND Use Promethazine HCl and codeine phosphate oral Remedy is a mix of codeine, an opioid agonist, and promethazine, a phenothiazine, indicated for that short-term aid of cough and upper respiratory signs or symptoms linked with allergy or the widespread cold in patients 18 decades of age and more mature. (one) (1)
Even though significant, existence-threatening, or fatal respiratory despair can arise at any time during the usage of promethazine HCl and codeine phosphate oral Remedy, the danger is biggest over the initiation of therapy, when promethazine HCl and codeine phosphate oral Alternative is used concomitantly with other prescription drugs that could lead to respiratory depression [see Warnings and Safeguards (five.
If you are taking codeine together with an excessive amount acetaminophen and acetylsalicylic acid (which are frequently put together with codeine), it can result in liver toxicity and gastrointestinal bleeding. These severe clinical disorders might cause the next symptoms:
Stay clear of the usage of promethazine HCl and codeine phosphate oral Option in individuals who're getting a CYP3A4 inhibitor, CYP3A4 inducer, or 2D6 inhibitor [see Warnings and
Notify your health practitioner When your cough isn't going to improve in 5 days. Also, convey to your medical professional When your ailment will get even worse, or When you have a headache that doesn't go away, fever, or rash. These could be signs of a significant clinical problem and will be checked by a doctor.
Fetal/Neonatal Adverse Reactions Extended usage of opioid analgesics during pregnancy for health-related or nonmedical functions can result in Bodily dependence within the neonate and neonatal opioid withdrawal syndrome Soon following start.
Talk to your Health care Expert about solutions to cough and chilly items that contains opioids for Your sons or daughters or adolescents.
Don't push, cycle or use equipment or machinery if you feel dizzy. GOV.United kingdom has more details on the regulation on medications and driving.